Chemical Structure of Vitamins and Minerals
Ever wondered more about the life supporting vitamins and minerals we depend on and never stop hearing about. This is definitely for the interested and/or nerdy.
Vitamins and minerals are nutrients required in very small amounts for essential metabolic reactions in the body. Some diseases caused by vitamin deficiencies, such as scurvy, have been recognized since antiquity, but it was only in the 20th century that systematic nutritional studies identified the chemical structures of many of these essential compounds. In 1913, Vitamin A was recognized for its importance in vision, and in 1932, Vitamin C was found to be necessary to prevent scurvy. The following paragraphs give some information about the most important vitamins and minerals.
MINERALS
The term “minerals” is applied to chemical elements present in the ash of calcined tissue. Dietary minerals may be present in inorganic salts, or as part of carbon-containing organic compounds. For example, magnesium is present in chlorophyll, the pigment that makes plants green. Six minerals are required by people in gram amounts: sodium (Na), potassium (K), calcium (Ca), magnesium (Mg), phosphorus (P), and chlorine (Cl). Daily requirements range from 0.3 to 2.0 grams per day. Nine trace minerals (microminerals) are required by people in minute amounts: chromium (Cr), copper (Cu), iodine (I), iron (Fe), fluorine (F), manganese (Mn), molybdenum (Mo), selenium (Se), and zinc (Zn). There are additional requirements for cobalt (Co), but these are generally expressed in terms of the cobalt-containing vitamin B12. All trace minerals are toxic at high levels.
The term Dietary Reference Intake (DRI) is used to represent daily dietary reference values such as Adequate Intake (AI), Tolerable Upper Intake Level (UL), Estimated Average Requirements (EAR), Nutrient Reference Value (NRV), and Recommended Dietary Allowance / Intake (RDA / RDI).
Calcium
Calcium (Ca) is the most abundant mineral in the human body. More than 99% of total body calcium is stored in the bones and teeth. Calcium is also found in body fluids where its function is to regulate contractions of blood vessels and muscles. The requirement for calcium is greatest from puberty to maturity, when the body grows very quickly. Milk and dairy products are good sources of calcium.
Age Calcium DRI (mg/day)
0-6 months 210
7-12 months 270
1-3 years 500
4-8 years 800
9-18 years 1300
19-50 years 1000
51+ years 1200
Fluorine
Most of the body’s fluorine (F) is contained in bones and teeth. The main source of fluoride is drinking water. Fluorine hardens tooth enamel and effectively prevents dental caries. Excessive fluorine in drinking water can accumulate in teeth and bones, causing fluorosis. Permanent teeth that develop during high fluorine intake have irregularly distributed chalky patches on the surface of the enamel which become stained yellow or brown, producing a characteristic mottled appearance.
Iodine
iodine (I) is primarily involved in the synthesis of two thyroid hormones, thyroxine and triiodothyronine. In adults, about 80% of the iodide absorbed is trapped by the thyroid gland.
Thyroxine
Most environmental iodine occurs in seawater. People living far from the sea are at particular risk of deficiency. Salt fortified with iodide (typically 70 μg/g) helps ensure adequate intake (100 μg/day). Deficiency is rare in areas where iodized salt is used but common worldwide. Iodine deficiency develops when iodide intake is less than 20 μg/day. In mild or moderate deficiency, the thyroid gland hypertrophies to concentrate iodide in itself, resulting in goiter which is an enlargement of the thyroid gland visible as a swelling of the front of the neck. Excessive iodine consumption can lead to thyrotoxicosis, a condition resulting from high concentrations of thyroid hormones in the body which can result from eating foods that have very high amounts of iodine, such as kombu-type kelp or seaweed.
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